Titlebook: 5-HT4 Receptors in the Brain and Periphery; Richard M. Eglen Book 1998 Springer-Verlag Berlin Heidelberg 1998 Pharmakologie.Signaltransduk

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Mitochondrial Damage in Traumatic CNS Injurycologically distinct mammalian 5-HT receptor subtypes (for reviews, see refs. 1, 2). This group of receptors possesses members of the putative seven transmembrane domain G-protein-coupled metabotropic receptor family and a member of the ligand-gated ion channel receptor family comparable to receptor

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Nikolaus Plesnila,Carsten Culmseen the enteric nervous system and endocrine cells of the gut. Enteric 5-hydroxytryptamine (5-HT) which accounts for a large proportion of the total body 5-HT,. is a key transmitter which exerts profound effects on various aspects of gastrointestinal function.. 5-HT, which can be released from either

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Marta M. Vieira,Ana Luísa Carvalho adrenal cortex through multiple actions at different levels of the hypothalamo-pituitary adrenal (HPA) axis (for a review see ref. 2). In the central nervous system, 5-HT stimulates corticotropin-releasing hormone (CRH) released from hypothalamic neurons . 5-HT also triggers adrenocorticotropin (AC

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Marta M. Vieira,Ana Luísa CarvalhoT. receptor activation. and to antagonism at dopamine D. and/or 5-HT. receptors.. However, since antagonism at dopamine D. receptors within the striatum may also cause extrapyramidal reactions and akathisia, alternative 5-HT. receptor agonists have been developed, with lower affinity for the D. rece

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Mitochondrial Damage in Traumatic CNS Injuryptor is the only member of its class because it shows little amino acid sequence relationship to all other serotonin receptors, including those positively coupled to the adenylyl cyclase (AC) (the 5-HT. and 5-HT. receptors)..

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https://doi.org/10.1007/978-3-319-77495-4 receptors regulate the electrophysiological properties of individual neurons; thus in turn, the functioning of neuronal networks. It is ultimately the effect of 5-HT. receptors on the functioning of these networks that impact behavioral and thought processes.

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Marta M. Vieira,Ana Luísa Carvalhoeflux (heartburn; mild esophagitis), functional or nonulcer dyspepsia and gastroparesis (e.g., caused by diabetic neuropathy).. For both drugs, the most common side-effect attributed to 5-HT. receptor activation is the promotion of loose stools and in more severe cases, diarrhea and abdominal pain.

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